Instructions before the treatment
INSTRUCTIONS FOR PATIENTS WHO WANT TO USE DR. COIMBRA’S PROTOCOL OF EXTREME HIGH DOSES OF VITAMIN D3
Scientific studies have shown that the human organism needs more vitamin D3 than it was previously thought. Today, outdated recommendations about taking up to 4000 I.U. of vitamin D3 per day are still in use.
However, plenty of new studies show that large percentage of people lack in vitamin D3. The most common cause is insufficient exposure to sunlight.
About 15% people have a genetic predisposition for inefficient production, transmission or activation of vitamin D, or response of Vit D3 receptors in the cells, so they suffer from insufficiency even if they are exposed to the sun. It was shown that they often suffer from autoimmune diseases in which the immune sistem develops Th17 cell inflammatory immunologic reaction, which attacks its own tissue.
Whereas vitamin D is involved in a large number of cellular responses, new studies indicate that adequate vitamin D supplementation is crucial in the treatment of these diseases. If the large doses of vit D3 are given to the patient for a long period, this kind of inflammation slowly calms down.
In order to calm down the Th17 autoimmune reaction, very high doses of vitamin D are required, about 1000 I.U. per kilogram each day, it means 25 μg (microgram) a day for 1 kg of patient’s body mass ( 1μg of vitamin D3 is 40 International Unites – I.U.).
If the patient takes this quantity of vit D, there is a significant increase of calcium absorption from food that patient has eaten.
IT MAY CAUSE ABNORMALLY HIGH CONCETRATION OF CALCIUM IN THE BLOOD AND CONSEQUENT DAMAGE TO THE KIDNEYS, UP TO IRREVERSIBILE NECESSITY OF DIALYSIS.
This is the main cause why doctors avoid using high doses of vitamin D.
Dr. Cicero Coimbra, a professor and neurologist from Brazil, and his team have been researching very high doses of vitamin D since 2004. They were gradually increasing doses controling all parametrs and in recent 5 years they have found out that the best dosage is about 1000 I.U./kg of patient’s body mass.
Diet prescribed must be folowed 100%.
They are treating and following about 4,000 patients. Up to date (June 2016), Dr. Coimbra has trained about 50 doctors in the world who treat patients using his protocol.
The problem of increasing calcium in the blood is avoided with adequate diet based on a reduced intake of calcium.
Dairy products, nuts and seeds are strictly forbidden.
It is necessary to avoid water which contains high levels of calcium, and food with added calcium. This diet is described in details in other attachment where Dr. Coimbra gives advice to patient that wishes to folow his protocol.
If the patient doesn’t follow these instructions, he/she can develop irreversible kidney damage and possible need for dialysis.
The dose of vitamin D is determined by the concentration of calcium in the blood and other results.
To be able to determine the quantity of vit D for specific patient, and other supplements according to protocol of Dr. Coimbra for autoimmune diseases, it is necessary to provide the following data:
Year of birth
Height
Weight
Race
Place where you currently live (to determine the quantity of sunlight during the year)
Complete blood count
Creatinine and urea in the serum
Glomerular filtration rate
Total and ionized calcium in serum
Calcium in 24 hour urine
Phosphorus in the serum
Phosphorus in 24 hour urine
Bone alkaline phosphatase ( If possible, if not general alcaline phosphatase )
Liver enzymes – AST,ALT,GGT
PTH in blood
Vitamin 25 (OH) D levels
Vitamin B12
Zinc
TSH
If medical findings were done within two months, it’s not necessary to repeat them.
Please, describe your health briefly, other diseases and medications you take.
The first control is usually done after one month and includes the test of calcium in the blood which should be submitted via e-mail. If it is within reference range, the patient continues the therapy for nexth 2 months. At that moment patient should make folowing laboratory tests:
PTH
Ionised calcium
Calcium in the serum
Calcium in 24 hours urine
Urea
Kreatinine
Phosphorus in the serum
Phosphorus in 24 hours urine
This control procedure may be modified if the patient’s condition requires it.
Within 6 months, patient has to make densitometry, a medical diagnostic procedure which describes bone density in order to follow it through longer period. This is especially important for patients with moving disabilities.
If there is osteopenia or osteoporosis it is important to exercise every day. If patient is immobile, he shuold ask his doctor to prescribe him Alendronate.
It is expected that most doctors will think that this way of treatment is dangerous. It certainly would be if you do not strictly stick to the diet, and control the level of calcium in the blood and urine, along with some other laboratory tests.
Please, watch the interview with Dr. Coimbra about MS and other autoimmune diseases which are treated by extremely high doses of vitamin D, also “Instructions for patients on high doses of vitamin D.”